Seasonal allergies can feel relentless in the Midlands. Symptoms can flare up after spending time outside at Lynch’s Woods Park in Newberry or along the shores of Lake Murray, where tree and grass pollen are common. If antihistamines and sprays aren’t bringing the kind of relief you need, allergy immunotherapy may be worth considering.
At Carolina Pines ENT, we believe patients do best when they understand their options. If you’re considering allergy immunotherapy, you should know that there are two different types: allergy shots and sublingual drops. Here’s a breakdown of the differences between the two, including timelines, pros and cons and what to expect.

What Is Allergy Immunotherapy?
Immunotherapy treats the cause of allergies, not just symptoms. After allergy testing identifies your triggers (like pollen, mold or dust mites), your body is gradually exposed to small, controlled amounts to help your immune system become less reactive over time. This can mean fewer symptoms, less medication and long‑lasting relief.
Allergy immunotherapy follows a structured schedule with two phases:
- Build‑up phase, which lasts a few months. The dosage is gradually increased during the build-up phase until you reach the maximum dose.
- Maintenance phase, which starts when you reach the maximum dosage. During this phase, the dosage is no longer increased. This continues for three to five years.
Allergy Shots vs. Allergy Drops: What’s the Difference?
Allergy Shots (Subcutaneous Immunotherapy)
Allergy shots are injections given in the office. During the build-up phase, you’ll come in for a shot once or twice a week. During the maintenance phase, this goes down to once a month.
Symptoms will typically improve over the first year of treatment and continue to improve over the next few years. The shots may even decrease symptoms for other allergens and prevent new allergies from developing.
Allergy Drops (Sublingual Immunotherapy)
Allergy drops work similarly to shots but are taken orally. They are taken at home rather than at a doctor’s office, making them more convenient for many patients, including those who cannot tolerate injections.
Is Immunotherapy Right for You?
Immunotherapy may be considered when:
- Allergy symptoms continue despite medications and avoidance strategies
- Long‑term symptom reduction is a goal
- Specific allergens have been identified through testing
Take the Next Step
If allergies are interfering with your daily life, the team at Carolina Pines ENTcan help determine whether allergy shots or sublingual drops are appropriate for you. Request an appointment to begin your personalized care journey.
